Stimulation of Facial Retention Points with Platelet-Rich Plasma in Female Patients Aged 30 to 50 Years in Santa Rosa, Misiones (2023–2024)

Authors

  • Augusto Rodrigo Ortiz Gómez Universidad Nacional de Caaguazu, Facultad de Ciencias Médicas, Especialización en Medicina Estética y Envejecimiento Fisiológico, Coronel Oviedo, Paraguay. https://orcid.org/0009-0008-7787-1345

Keywords:

Platelet-rich plasma, facial rejuvenation, skin aging, biostimulation

Abstract

Introduction: Platelet-rich plasma (PRP) is widely used in aesthetic medicine due to its biostimulatory effects on skin regeneration and improvement of aging signs.

Objective: To evaluate the effects of PRP stimulation on facial retention points in female patients aged 30 to 50 years.

Materials and Methods: Observational, descriptive study including 30 patients treated in a private clinic in Santa Rosa, Misiones (2023–2024). Sociodemographic variables, aging signs, skin texture and color changes, satisfaction, and adherence were analyzed.

Results: Mean age was 40 years. Aging signs were present in 44% of patients. Texture changes were observed in 40%, and hyperpigmentation in 57%. A total of 79% reported excellent satisfaction, and 54% showed excellent adherence.

Conclusion: PRP applied to facial support points proved to be a safe and effective treatment with high satisfaction and adherence, improving clinical signs of facial aging.

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References

1. Eppley BL, Pietrzak WS, Blanton M. Platelet-rich plasma: a review of biology and applications in plastic surgery. Plast Reconstr Surg. 2006;118(6):147e–159e. doi:10.1097/01.prs.0000239606.92676.cf

2. Alves R, Grimalt R. A review of platelet-rich plasma: history, biology, mechanism of action, and classification. Skin Appendage Disord. 2018;4(1):18–24. doi:10.1159/000477353

3. Andia I, Abate M. Platelet-rich plasma: underlying biology and clinical correlates. Regen Med. 2013;8(5):645–658. doi:10.2217/rme.13.59

4. Conde Montero E, Fernández Santos ME, Suárez Fernández R. Platelet-rich plasma: applications in dermatology. Actas Dermosifiliogr. 2015;106(2):104–111. doi:10.1016/j.ad.2013.12.021

5. Piipponen M, Li D, Landén NX. The immune functions of keratinocytes in skin wound healing. Int J Mol Sci. 2020;21(22):8790. doi:10.3390/ijms21228790

6. Wang Z, Feng C, Chang G, Liu H, Li S. The use of platelet-rich plasma in wound healing and vitiligo: a systematic review and meta-analysis. Skin Res Technol. 2023;29(9):e13444. doi:10.1111/srt.13444

7. Magruder ML, Caughey S, Gordon AM, Capotosto BSS, Rodeo SA. Trends in utilization, demographics, and costs of platelet-rich plasma injections: a ten-year nationwide investigation. Phys Sportsmed. 2024;52(1):89–97. doi:10.1080/00913847.2023.2178816

8. Matz EL, Scarberry K, Terlecki R. Platelet-rich plasma and cellular therapies for sexual medicine and beyond. Sex Med Rev. 2022;10(1):174–179. doi:10.1016/j.sxmr.2020.07.001

9. Wei W, Zhang Y, Long B, Zhang Y, Zhang C, Zhang S. Injections of platelet-rich plasma combined with topical 5% minoxidil in androgenetic alopecia. Skin Res Technol. 2023;29(7):e13315. doi:10.1111/srt.13315

10. Li ZJ, Choi HI, Choi DK, Sohn KC, Im M, Seo YJ, et al. Autologous platelet-rich plasma: a potential therapeutic tool for promoting hair growth. Dermatol Surg. 2012;38(7 Pt 1):1040–1046. doi:10.1111/j.1524-4725.2012.02394.x

11. Dankova I, Pyrgidis N, Tishukov M, et al. Efficacy and safety of platelet-rich plasma injections for female sexual dysfunction: a systematic review. Biomedicines. 2023;11(11):2919. doi:10.3390/biomedicines11112919

12. Wu CC, Wu YN, Ho HO, Chen KC, Sheu MT, Chiang HS. The neuroprotective effect of platelet-rich plasma on erectile function. J Sex Med. 2012;9(11):2838–2848. doi:10.1111/j.1743-6109.2012.02881.x

13. Wu YN, Wu CC, Sheu MT, Chen KC, Ho HO, Chiang HS. Optimization of platelet-rich plasma and erectile function recovery. J Tissue Eng Regen Med. 2016;10(10):E294–E304. doi:10.1002/term.1806

14. Andia I, Rubio-Azpeitia E, Martin JI, Abate M. Current concepts and translational uses of platelet-rich plasma biotechnology. In: Deniz E, editor. Biotechnology. IntechOpen; 2015. doi:10.5772/58927

15. Velarde MC, Flynn JM, Day NU, Melov S, Campisi J. Mitochondrial oxidative stress promotes skin aging phenotypes. Aging (Albany NY). 2012;4(1):3–12. doi:10.18632/aging.100423

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Published

2026-05-19

How to Cite

1.
Ortiz Gómez AR. Stimulation of Facial Retention Points with Platelet-Rich Plasma in Female Patients Aged 30 to 50 Years in Santa Rosa, Misiones (2023–2024). Cienc. Est. [Internet]. 2026 May 19 [cited 2026 May 25];2(1):1-7. Available from: https://www.cienciayestetica.org/index.php/revista/article/view/18

Issue

Vol. 2 No. 1 (2026): Enero - Abril

Section

Artículos originales

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Copyright (c) 2026 Augusto Rodrigo Ortiz Gómez

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This work is licensed under a Creative Commons Attribution 4.0 International License.